Bisphosphonate osteonecrosis of the jaw: a literature review of UK policies versus international policies on the management of bisphosphonate osteonecrosis of the jaw.
نویسندگان
چکیده
Despite the increasing number of cases of osteonecrosis of the jaws related to bisphosphonate therapy described in the literature there is a paucity of evidence-based treatment for the condition. In this second article on bisphosphonate-related jaw complications we discuss the different treatment strategies for the condition, review current literature, particularly in relation to the recommendations that have been published, and discuss the evidence behind them.
منابع مشابه
isphosphonate osteonecrosis of the jaw—a literature review f UK policies versus international policies on isphosphonates, risk factors and prevention
here has been an exponential rise in the literature of osteonecrosis and its complications in patients taking bisphosphonate drugs. Despite this ncrease, there is little evidence-based publications on how best to manage this complication. In this article (the first of two on bisphosphonate elated jaw complications), we compare the guidelines produced by national specialist medical associations ...
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Bisphosphonates are a class of agents used to treat osteoclast-mediated bone diseases and many neoplasm types. Osteonecrosis of the jaw is a common side effect of bisphosphonate therapy, presenting as exposed and necrotic maxillary and/or mandibular bone. In this report, we present a case of bisphosphonate-related osteonecrosis of the jaw in a patient who received oral alendronate therapy due t...
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Osteonecrosis of the jaw in patients treated with bisphosphonates is a relatively rare but well known complication at maxillofacial units around the world. It has been speculated that the medication, especially long-term i.v. bisphosphonate treatment, could cause sterile necrosis of the jaws. The aim of this narrative review of the literature was to elaborate on the pathological mechanisms behi...
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We describe the cases of three patients, under the care of the rheumatology service, who presented with osteonecrosis of the jaw whist on oral bisphosphonate therapy. The first case is of a 74-year-old woman with a 12 year history of sero-negative inflammatory arthritis, having been on oral steroids for 11 years, Methotrexate for the preceding 6 years, and oral bisphosphonates for 9 years. Clin...
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ورودعنوان ژورنال:
- The British journal of oral & maxillofacial surgery
دوره 49 5 شماره
صفحات -
تاریخ انتشار 2011